Hi Dawn,
Just to add more on my findings on this, Please make sure with your basis and/or technical team that all following four SAP Notes are in the system now:
1802903
1810094
1810101
1821967
They altogether taking care of adding new tab in ES64, providing BADI's if any new logic needs to installed, and replication to CRM system when change takes place in IS-U.
Thanks,
Mandeepak